PurO3 Toe & Nail Formula was created to deliver the antifungal powers of ozonated sunflower oil directly to the affected toe and nails. PurO3 Toe and Nail Support is made from fully ozonated organic sunflower oil and is combined with DMSO, MCT oil, turpentine and ozonated coconut oil. It comes with an easy-to-use applicator brush for proper application. When the ingredients are combined, PurO3 Toe and Nail formula creates perfect synergistic effects to help eliminate unhealthy fungal issues on the toes and nails.






What Our Customers Love
Miracle
“The toe and nail support is amazing, it started working after just a couple of applications. Way more effective and natural than prescription.”
- Anon
Excellent Formulation
“Toenail fungus is difficult to deal with no matter what you use. I've tried everything and I'm still dealing with it for years. Toe & Nail Support from PurO3 is the most on target product I've seen for this problem and after using it for several weeks, I feel it's starting to make a difference."
- Anon
PurO3 Toe & Nail Formula was created to deliver the antifungal powers of ozonated sunflower oil directly to the affected toe and nails.
Ozonated sunflower oil has been shown to inhibit fungal and bacterial growth. Ozone works by attaching itself to the cell walls of the microorganisms and splitting them apart. This action essentially kills the fungus or bacteria. Fungi and bacteria are unable to develop resistance to ozone, unlike other antifungal or antibacterial medications, making ozone a preferred long-term method.
DMSO is a delivery agent and helps push the ozonated sunflower oil deeper so it can penetrate the skin and nail bed. In addition, DMSO creates an unfavorable environment to help prevent the replication process of fungi and bacteria.
MCT Oil creates an ideal consistency so ozonated sunflower can easily be absorbed. MCT oil contains a large amount of caprylic acid, which has been shown to provide antifungal and antimicrobial effects. In addition, fungus cannot replicate in an acidic environment.
Turpentine is a powerful antifungal agent that easily absorbs through the skin, making it an ideal ingredient for controlling fungal issues. PurO3 uses 100% pure gum spirits distilled directly from raw pine gum rosin. It is not a byproduct of the pulp industry and is made in America.
Simple, safe, and pure
At PurO3, we believe that what you put on your body should be as clean and honest as what you put in it. That’s why we craft every product with a short list of organic, plant-based ingredients and infuse them with activated oxygen (ozone) using a low-heat, proprietary process that protects their natural integrity. There are no fillers, no synthetic fragrances, and no harsh preservatives—just powerful simplicity backed by science. Our formulas are designed for families, wellness seekers, and anyone looking to keep their routine safe, simple, and pure, without sacrificing results.
Why choose PurO3?
We believe that true wellness comes from transparency, trust, and thoughtful craftsmanship. That’s why we do something most brands don’t—we make everything ourselves. Unlike companies that outsource their manufacturing, we formulate, infuse, and package every product in our own ozone lab, giving us full control over purity, potency, and consistency from start to finish. This hands-on approach lets us fine-tune every step—from the use of ultrapure oxygen to our gentle, low-heat infusion process—ensuring that what you’re putting on your body is as fresh, effective, and clean as possible.
Our process
PurO3 products are created daily in our Fayetteville, Arkansas headquarters. Our reactor room is state-of-the-art, staffed with highly trained local artisans, adhering to strict quality control guidelines.
Our mission is simple: to provide natural products with a do-no-harm ethos, backed up with education, transparency, customer service, and trust. We serve you and the planet, not the latest trends.
- Fully ozonated oils
- Certified organic ingredients
- Cold ozone production with a high-purity oxygen source
- Glass packaging
- Refrigerated storage
- Pure: No fillers, stabilizers, GMOs, preservatives, or binders
- 100% all natural and safe: No hidden ingredients
- Made in the USA
Frequently Asked Questions
How many times a day do you recommend using Toe & Nail Support?
We recommend using it a minimum of two times per day. Using more than twice per day will only increase the results.
How fast does the PurO3 Toe and Nail support absorb?
PurO3 Toe and Nail Support is oil-based and will take several minutes to absorb. We recommend waiting a few minutes before putting on socks and shoes.
How does PurO3 Toe and Nail support work?
PurO3 combines ozonated sunflower oil, DMSO, and turpentine to drive past the skin and nail bed. This helps fight whatever is causing the issue.