PurO3’s Probiotic Suppositories offer a powerful, targeted approach to supporting gut health and balancing microbiota. Each suppository combines 18 beneficial probiotic strains with certified organic cocoa butter, which is rich in vitamins, minerals, and antioxidants to enhance the absorption and effectiveness of the probiotics. With 50.7 billion CFU per suppository, these probiotics directly target intestinal flora imbalances, bypassing the digestive system for more efficient delivery. This makes them a superior option compared to oral supplements, which can lose efficacy due to stomach acids.





What Our Customers Love
Great for premenopausal women
“I love these. Being premenopausal I was having trouble getting my ph to balance. These are a total GameChanger! I have used almost all of PurO3 suppositories and have had nothing but great experience in my healing journey. So grateful for this company.”
- Heather
Huge help!
“These have been awesome! Really helpful in getting my candida in check. Most of these strains were recommended in my gut zoomer but my oral probiotics weren’t having much effect. So thankful I tried this. I’m no longer constipated and don’t use any bowel support except aloe Vera. I’ve only used this for 9 days. Amazing!”
- Anon
PurO3’s probiotic suppositories are a multi-strain combination mixed with natural cocoa butter.
Our cocoa butter is certified organic and naturally contains vitamins, minerals, and bioflavonoids with antioxidant properties. This serves as a base for our combination of 18 strains of beneficial bacteria along with a prebiotic.
Each package contains your choice of 10 or 20 suppositories. This product is not ozonated. Each suppository contains 50.7 billion CFU (colony-forming units).
The benefit of using a suppository is that the total dosage of probiotics goes to the source of intestinal flora imbalance without having to be digested. When taken orally, anywhere from 1/2 to 3/4 or more of the strains do not make it past the stomach acids. Suppositories are a solution to this problem.
Probiotic suppositories are used to help reestablish gut flora, help diminish vaginal yeast infections and bacterial infections of BV (bacterial vaginosis), and may help prevent recurring urinary tract infections.
More about Probiotics
Our intestines contain a rich supply of blood vessels that actively exchange substances, and mucous membranes that harbor vast communities of functional bacteria. Numerous studies have examined the complex mechanisms of the beneficial effects of probiotics. Bacteria help create a protective lining on the walls of the intestine by stimulating the production of mucus and regulating adherence by certain bacteria. This helps support a proper balance of microbiota in the gut. Antimicrobial peptides, or bacteriocins, are produced by these bacteria and establish competitive exclusion of pathogenic strains. Each suppository contains 50.7 billion CFU (colony-forming units).
Frequently Asked Questions
Can these be used both rectally and vaginally?
Yes, the probiotic suppositories can be used both rectally and vaginally.
How does this compare to an oral probiotic?
Administering probiotics rectally can bypass the harsh conditions of the stomach and digestive tract. This can help deliver probiotics directly to the colon where they have a better chance to repopulate.
What does it mean when you say 50 billion CFUs per suppository?
50 billion CFUs means there are an estimated 50,000,000,000 live microorganisms in each individual suppository.